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I'd put this down as a comment, but don't have the reputation to do so. There is (or at least used to be) a two part MOOC course over at Coursera by one of the developers of QuantSoftware Toolkit. This is not an endorsement of the course or the software, just a statement of fact (for the record, I did do a part of the course, but found it too simplistic and ...
You can download the time series of e.g. S&P500 prices from NYSE, then their dates should well represent approximately the real NYSE trading days.
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