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You can do this using the optim function in R. One possible solution is as follows: base <- c(0.9190, 0.0739, 0.0072, 0.0000, 0.0000, 0.0000, 0.0000, 0.0000, 0.0113, 0.9126, 0.0709, 0.0031, 0.0021, 0.0000, 0.0000, 0.0000, 0.0010, 0.0256, 0.9119, 0.0533, 0.0062, 0.0021, 0.0000, 0.0000, 0.0000, 0.0021, 0.0536, 0.8794, ...



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