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Speaking from equity quant factor building experience, it is a common practice to build multi-factor models by regressing one component against other(s) and using the residual scores. This is done to avoid bias as you mentioned - these biases could be from the factor itself (in different regimes, Quality / Momentum influencing each other - or earnings, value ...


If you are investing an amount $M$, split over deals indexed by $i$ and with a weight $w_i$, then your dollar position in each share will be $w_i M$. The exposure to the index will be $\sum \beta_i w_i M$ You should realize that this will not hedge idiosyncratic risks. In general, the more deals you have, the better this type of hedge should work (assuming ...

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