I work in a relatively illiquid and old-fashioned market (options on power), where trades are arranged via phone & broker, so the issue of low underlying liquidity is definitely there. To remedy this, all options are dealt with delta hedge, where the price level of the delta hedge is pre-agreed, so market moves during arrange a trade do not matter as much (unless of course they are very substantial).
In your case, I would refer to end-of-day quotes, where in the case of exchange-traded options, you have closing prices for options and futures. In this case, the exchange will probably poll several dealers in order to give a realistic market picture. In OTC markets, brokers will show end of day option rates, and explicitly reference them to a closing price of the underlying.
As for judging the mode of behaviour (sticky strike vs. sticky delta) intraday, I would be cautious. Imho, if you base your hedging decisions on this, you may overengineer, potentially not doing yourself a favour.
I have mostly been working on the assumption that a rangebound market with very modest moves will be sticky strike, whereas during more volatile periods it will behave in a sticky-delta way. Not having tested this explicitly, I would say you could try to look for a criterion along the lines of:
$S\sigma/\sqrt{252}\gg\mathit{daily move}$ (sticky strike) resp. $S\sigma/\sqrt{252}\ll\mathit{daily move}$ (sticky delta)
What you could do to make this into a more sound methodology is to run volatility analysis on end-of-day data and relate to daily moves.