First, my notation. $K$ is the strike price, $S$ is the stock price, $r$ is the continuously compounded risk-free rate, $T$ is time at expiration, $t$ is time at issue, $\sigma$ is volatility, $\delta$ is continuously compounded dividend rate.
The Black-Scholes formula for a European call is
$C = Se^{-\delta (T-t)} N(d_1) - Ke^{-r(T-t)} N(d_2)$
$d_1 = \dfrac{\ln(S/K) + (r - \delta + 0.5\sigma^2)(T-t)}{\sigma \sqrt{(T-t)}}$ and $d_2 = d_1 - \sigma \sqrt{(T-t)}$.
Some common greeks are
$\Delta$ = $\dfrac{ \partial C}{\partial S}$, $\Gamma = \dfrac{ \partial^2 C}{\partial S^2}$, $\rho = \dfrac{\partial C}{\partial r}$, $v = \dfrac{\partial C}{\partial \sigma}$, $\theta = \dfrac{\partial C}{\partial t}$ and $\psi = \dfrac{\partial C}{\partial \delta}$.
Note that $\theta$ is often equivalenty defined as $- \dfrac{\partial C}{\partial T}$. You can derive the greeks by taking the partial derivatives.
As an example, I will derive $\Delta = e^{-\delta (T-t)} N(d_1)$
\begin{align*}
\Delta &= \dfrac{\partial C}{\partial S} \\
&= e^{-\delta (T-t)} N(d_1) + \dfrac{\partial C}{\partial S} Se^{-\delta (T-t)} N(d_1) - \dfrac{\partial C}{\partial S} Ke^{-r(T-t)} N(d_2) \\
&= e^{-\delta (T-t)} N(d_1)
\end{align*}
It is not obvious that the last two terms cancel out. I prove this below.
\begin{align}
&\dfrac{\partial C}{\partial S} Se^{-\delta (T-t)} N(d_1) - Ke^{-r(T-t)} N(d_2) \\ &= Se^{-\delta (T-t)} \dfrac{\partial}{\partial S} d_1 \dfrac{1}{\sqrt{2\pi}} e^{-0.5d_1^2} - Ke^{-r(T-t)} \dfrac{\partial}{\partial S} d_2 \dfrac{1}{\sqrt{2\pi}}e^{-0.5d_2^2} \\
&\propto \dfrac{\partial}{\partial S}d_1 \left( Se^{-\delta (T-t)} e^{-0.5d_1^2} - Ke^{-r(T-t)} e^{-0.5 d_2^2} \right) \\
\end{align}
Note that
\begin{align*}
&\ln\left(Se^{-\delta(T-t)}e^{-0.5d_1^2}\right) - \ln\left(Ke^{-r(T-t)} e^{0.5d_2^2} \right) \\ &= \ln(S) - \delta(T-t) - \ln(K) + rT + 0.5d_2^2 - 0.5d_1^2 \\
&= \ln(S/K) + (r-\delta)(T-t) - 0.5(d_1^2 - (d_1 - \sigma\sqrt{T-t})^2) \\
&= \ln(S/K) + (r-\delta)(T-t) - 0.5(2d_1\sigma\sqrt{T-t} - \sigma^2(T-t)) \\
&= \ln(S/K) + (r-\delta)(T-t) - d_1 \sigma\sqrt{T-t} + 0.5\sigma^2(T-t) \\
&= \ln(S/K) + (r-\delta)(T-t) - \left(\ln(S/K) + (r-\delta + 0.5\sigma^2)(T-t)\right) + 0.5\sigma^2(T-t)
\end{align*}
So $\left( Se^{-\delta (T-t)} e^{-0.5d_1^2} - Ke^{-r(T-t)} e^{-0.5 d_2^2} \right) = 0$ and $\Delta$ = $e^{-\delta(T-t)} N(d_1)$ as shown above.
Note that $\Delta > 0$ for a European call. Hedging greeks is a common topic in financial economics. To hedge a European call, short sell $\Delta$ shares of stock. This protects a portfolio against small changes in the stock price.
EDIT 1
By the BSE, $V_t + 0.5V_ss(\sigma S)^2 = rV - VsS(r-\delta)$ can be written as $\theta + 0.5\Gamma(\sigma S)^2 = rV - \Delta S(r-\delta)$. The solution to the BSE depends on the terminal conditions and payoff.